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Spinal cord stimulation for multiple sclerosis: quantifiable benefits.

R Davis1, S E Emmonds

  • 1Section of Neurosurgery, Veterans Administration Medical Center, Augusta, Me.

Stereotactic and Functional Neurosurgery
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

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Spinal cord stimulation (SCS) improved function in multiple sclerosis (MS) patients, enhancing hand strength and mobility. Early SCS intervention may offer rehabilitation benefits for MS patients experiencing functional decline.

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Medical Engineering

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease causing progressive deterioration.
  • Functional decline in MS significantly impacts patients' quality of life and independence.
  • Limited rehabilitation options exist for managing MS-related weakness and mobility issues.

Purpose of the Study:

  • To quantitatively assess the benefits of epidural spinal cord stimulation (SCS) in patients with multiple sclerosis.
  • To evaluate the impact of SCS on hand function, muscle strength, and ambulation in MS patients.
  • To determine the potential of SCS as an early rehabilitation strategy for MS.

Main Methods:

  • A quantitative study involving 5 MS patients (36-45 years old) with 12-22 years of symptoms.

Related Experiment Videos

  • Epidural SCS was applied at the C7-T1 level, with 4-8 testing sessions before and during stimulation.
  • Functional outcomes were measured using hand dynamometry, Jebson Hand Time Testing, Minnesota Manipulation Testing, manual muscle strength, and parallel bar ambulation.

    • Main Results:

    • Spinal cord stimulation (SCS) led to significant improvements in hand function (2- to 4-fold increase in grip strength) and dexterity.
    • Manual muscle strength increased by 20-50% in all patients.
    • Ambulation improved in wheelchair-bound patients, and one hemiparetic patient could walk without a cane.
    • Despite initial improvements, a slow functional deterioration was observed over the study duration.

    Conclusions:

    • Epidural spinal cord stimulation (SCS) demonstrates quantifiable benefits for multiple sclerosis patients with functional deficits.
    • SCS can enhance hand function, muscle strength, and mobility, offering a potential rehabilitation option.
    • Early implementation of SCS is recommended for MS patients to maximize benefits before significant disease progression.