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Phenotypic analysis of functionally associated molecules on peripheral blood and synovial fluid monocytes from
S J Gadd1, T Felzmann, O Majdic
1Institute of Immunology, University of Vienna, Austria.
Rheumatology International
|January 1, 1992
Abstract:
Surface expression of 16 different membrane molecules was analyzed in peripheral blood and synovial fluid monocytes from patients with rheumatoid arthritis and reactive arthritis compared to controls. The most significant findings were modulated expression of function-associated FcRI, CR1, CR3, MHC class II and activation-associated CD31, M5, and M6 molecules in arthritis patients compared to controls. Of these molecules, only upregulated expression of MHC class II has previously been reported in synovial fluid monocytes of patients with rheumatoid arthritis.