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Related Experiment Video

Updated: Mar 14, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Treat-to-target (T2T) recommendations for gout.

U Kiltz¹, J Smolen², T Bardin³

¹Rheumazentrum Ruhrgebiet, and Ruhr University Bochum, Herne, Germany.

Annals of the Rheumatic Diseases

|September 24, 2016

Summary

This study developed the first international treat-to-target (T2T) recommendations for gout management. The guidelines focus on normalizing serum urate levels to reduce chronic pain and inflammation, improving patient outcomes.

Keywords:

Gout Qualitative research Treatment

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Area of Science:

Rheumatology
Gout Management
Inflammatory Diseases

Background:

Gout is a chronic inflammatory disease characterized by high serum urate levels.
The treat-to-target (T2T) concept has proven effective in managing other rheumatic diseases.
Applying T2T to gout is logical due to its strong link with serum urate levels.

Framework:

Developed four overarching principles for gout management.
Established nine treat-to-target (T2T) recommendations for gout.
Focused on achieving normal serum urate levels as a primary target.

Implementation:

Expert consensus guided the development of T2T recommendations.
Systematic literature review informed the evidence base.
Recommendations were based on indirect evidence and expert agreement.

Implications:

These represent the first T2T recommendations specifically for gout.
The principles emphasize crystal dissolution and flare prevention.
Patient education, medication adherence, and serum urate monitoring are crucial.