Effects of absence of saliva on blood feeding by mosquitoes

Science (New York, N.Y.)
|June 10, 1960
PubMed

Insights

The salivary glands of Aedes stimulans mosquitoes contain an antigen causing bite reactions. Cutting the salivary duct prevents these reactions, suggesting saliva

Area of Science:

  • Entomology
  • Immunology
  • Vector-borne Diseases

Background:

  • Aedes stimulans mosquitoes are known vectors.
  • Mosquito bites can elicit reactions in hosts.
  • The specific components of mosquito saliva responsible for host reactions are not fully understood.

Purpose of the Study:

  • To identify the source of antigens responsible for Aedes stimulans bite reactions.
  • To investigate the role of mosquito saliva in eliciting host responses.
  • To determine if saliva is essential for blood feeding and subsequent egg development.

Main Methods:

  • Studied the salivary glands of Aedes stimulans.
  • Performed experiments involving cutting the main salivary duct of the mosquito.
  • Observed and recorded host reactions (in humans and rabbits) following mosquito bites.
  • Assessed blood intake and egg development in mosquitoes with and without intact salivary ducts.

Main Results:

  • Salivary glands of Aedes stimulans produce an antigen that causes typical bite reactions.
  • Cutting the main salivary duct prevented the elicitation of bite reactions.
  • Saliva was not essential for blood meal uptake, blood flow to the mid-gut, or egg development.

Conclusions:

  • The antigen responsible for Aedes stimulans bite reactions originates from the salivary glands.
  • Saliva plays a critical role in the host's bite reaction.
  • An anesthetic component in the saliva of Aedes stimulans is suggested.