[Isolation and physico-chemical characteristics of ceruloplasmin obtained from murine serum]

Ceruloplasmin was isolated from mice blood serum by means of ion exchange chromatography and gel filtration. Its content in blood was equal to 10-12 mg/100 ml, oxidase activity--9-12 U/mg of protein at E440, molecular mass--161.3 +/- 5.8 kDa. Properties of mice ceruloplasmin were studied as compared with the human and rat glycoprotein, isolated using the similar procedure.