Interpreting digoxin concentrations

In all cases, clinical assessment of the patient is the most critical factor in determining dose and interpreting concentrations. When done accurately, laboratory assessment of drug concentrations represents only one source of information. Serum concentrations must be taken into account along with all other relevant clinical data before one can arrive at appropriate management decisions. They must not be considered in isolation and out of context. If the laboratory report is at variance with your clinical judgment, "it will often be the better part of wisdom to question (or reject) the report."