Related Experiment Video
Updated: Jul 10, 2026

11:58
Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
Cerebral aneurysms in children
1Department of Neurosurgery Juntendo University School of Medicine, Tokyo, Japan.
Brain & Development
|July 1, 1992
Summary
Childhood intracranial aneurysms are rare but can cause serious subarachnoid hemorrhage (SAH). Repeated angiography is crucial for diagnosing these aneurysms, even if initial scans are negative.
Area of Science:
- Pediatric Neurosurgery
- Cerebrovascular Diseases
Background:
- Intracranial saccular aneurysms are uncommon in children, representing only 0.6-4.6% of all aneurysms.
- Spontaneous subarachnoid hemorrhage (SAH) in childhood is a rare but serious condition.
Observation:
- Two pediatric cases of intracranial aneurysms are presented: a 12-year-old boy with sudden severe headaches and a 3-year-old boy with an incidentally discovered aneurysm.
- Initial CT indicated SAH in the first case, but angiography initially failed to identify the aneurysm. Repeat angiography revealed a small aneurysm successfully treated with a miniclip.
- In the second case, CT incidentally revealed a large aneurysm of the middle cerebral artery, which was surgically clipped despite compromise of the prefrontal artery.
Findings:
- Repeated angiography is essential for diagnosing childhood aneurysms, especially when initial imaging is negative.
- Childhood aneurysms are increasingly detected incidentally via CT scans.
- Surgical outcomes for pediatric aneurysms can be favorable, though challenges like vessel compromise may occur.
Implications:
- This study highlights the importance of persistent diagnostic efforts in pediatric SAH.
- Understanding the unique characteristics of childhood aneurysms is vital for effective management.
- Early and accurate diagnosis through advanced imaging and repeated angiography improves surgical outcomes in pediatric cerebrovascular disease.
Related Concept Videos
Aneurysm I: Introduction
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Cerebral Edema l: Introduction
Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...
Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...

