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[Positive ventriculography with metrizamide (Amipaque)(author's transl)]
Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|November 1, 1977
Summary
Metrizamide (Amipaque) is a safe water-soluble contrast agent for ventriculography, yielding diagnostic imaging in most patients, including children. Minimal side effects were observed, with no significant complications reported.
Area of Science:
- Neuroradiology
- Medical Imaging
Background:
- Ventriculography is a neuroimaging procedure used to visualize the ventricular system of the brain.
- Water-soluble contrast media are essential for achieving diagnostic quality in such procedures.
Purpose of the Study:
- To evaluate the safety and efficacy of metrizamide (Amipaque) as a water-soluble contrast medium for ventriculography.
- To assess the diagnostic yield of metrizamide in visualizing the brain's ventricular system and surrounding structures.
Main Methods:
- Retrospective analysis of 27 patients undergoing ventriculography with metrizamide.
- Assessment of side effects and diagnostic image quality.
Main Results:
- No significant adverse events were observed in 27 patients (12 children).
- A transient, mild increase in CSF cell count resolved within days.
- Diagnostic imaging of ventricles, aqueduct, basal cisterns, and cerebellum was achieved in 24 patients.
Conclusions:
- Metrizamide (Amipaque) is a safe and effective contrast agent for ventriculography.
- It provides diagnostic information with minimal and transient side effects, even in pediatric patients.