[Specific immunity in patients with inflammatory diseases of the abdominal cavity]

In most patients with pyoinflammatory diseases of the abdominal cavity caused by Cl. perfringens microbial associations accumulation of agglutinins occurred during the disease. In purulent abdominal processes caused by Cl. perfringens microbial associations a connection exists between the increased antibody level and wound suppuration. The rise of the antibody level was most marked, whatever the character of the bacterial associations, in patients with generalized peritonitis, abdominal abscess, and in young patients (10-40 years of age) and least in those with phlegmonous cholecystitis and in elderly patients (61-70 years of age). Patients with destructive forms of appendicitis and individuals aged 41-60 took an intermediate position according to these values. Antibody production was weaker in patients with 5 species in the microbial association than in monoinfection. A agglutinin titer in the blood of patients beginning with 1:80 and higher should be considered diagnostic.