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Pseudallescheria boydii keratitis
1Department of Ophthalmology, Sir Charles Gairdner Hospital, Perth, Western Australia.
Abstract:
We treated a case of post-traumatic keratitis caused by the soil saprophyte, Pseudallescheria boydii. The injury was caused by a wood splinter which produced a perforating corneal laceration that was primarily repaired. Signs of corneal infection were not evident until the fourth postoperative week. The organism was eradicated by topical miconazole and natamycin. Subsequent penetrating keratoplasty combined with cataract extraction and intraocular lens implantation has achieved a good visual outcome.
Insights
A rare fungal eye infection, Pseudallescheria boydii keratitis, was successfully treated with antifungal medications. This case highlights effective management of post-traumatic corneal infections for good visual recovery.
Area of Science:
- Ophthalmology
- Medical Mycology
Background:
- Post-traumatic corneal infections can be challenging to manage.
- Fungal keratitis, particularly from soil saprophytes, requires prompt diagnosis and treatment.
Observation:
- A patient presented with a corneal laceration from a wood splinter, initially repaired surgically.
- Ocular infection with Pseudallescheria boydii manifested four weeks postoperatively.
Findings:
- Topical miconazole and natamycin effectively eradicated the Pseudallescheria boydii infection.
- Successful visual outcome was achieved after subsequent penetrating keratoplasty, cataract extraction, and intraocular lens implantation.
Implications:
- This case demonstrates the efficacy of specific antifungal agents in treating rare fungal keratitis.
- Aggressive surgical and medical management can restore vision in severe post-traumatic ocular fungal infections.
