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Updated: Aug 31, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
[Comparison of vascular risk factors profiles for transient ischemic attacks and ischemic stroke]
Adrià Arboix1, Elsa Solà, Marta Castillo
1Unitat de Patologia Vascular Cerebral, Servei de Neurologia, Hospital del Sagrat Cor Barcelona, España. aarboix@meditex.es
Background And Objective:
To determine vascular risk factor (VRF) profiles in transient ischemic attack (TIA) and ischemic stroke.
Patients And Method:
We studied 239 patients with TIA and 1,473 ischemic stroke patients included in a prospective stroke registry over a 10-year period.
Results:
Main VRF were: hypertension, hyperlipidemia, diabetes mellitus and atrial fibrillation. In the multivariate analysis, prior ischemic stroke (OR=1.65; 95% CI, 1.07-2.56), atrial fibrillation (OR=1.60; 95% CI, 1.14-2.26) and current use of warfarin treatment (OR=0.34; 95% CI, 0.13-0.94) were the only independent risk factors associated with ischemic stroke.
Conclusions:
Different potentially modifiable vascular risk factor profiles were identified in ischemic stroke versus TIA. This suggests that there are pathogenic differences between TIA and ischemic strokes.
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