Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Practical applications of chemical shift imaging.

T R Brown1

  • 1Fox Chase Cancer Center, Department of Nuclear Magnetic Resonance and Medical Spectroscopy, Philadelphia, PA 19111.

NMR in Biomedicine
|September 1, 1992
PubMed
Summary

Spectral localization methods are reviewed, highlighting phase encoding and frequency selective RF pulses. Chemical shift imaging (CSI) is detailed as a phase encoding technique, with its spatial accuracy and dimensional applications explored.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantitative Diffusion and Spectroscopic Neuroimaging Combined with a Novel Early-Developmental Assessment Improves Models for 1-Year Developmental Outcomes.

AJNR. American journal of neuroradiology·2021
Same author

Evaluation of a Preharvest Bacteriophage Therapy for Control of Salmonella within Bovine Peripheral Lymph Nodes.

Journal of food protection·2021
Same author

Reply.

AJNR. American journal of neuroradiology·2020
Same author

<i>Reply</i>.

AJNR. American journal of neuroradiology·2020
Same author

Evaluation of the Efficacy of Three Direct Fed Microbial Cocktails To Reduce Fecal Shedding of <i>Escherichia coli</i> O157:H7 in Naturally Colonized Cattle and Fecal Shedding and Peripheral Lymph Node Carriage of <i>Salmonella</i> in Experimentally Infected Cattle.

Journal of food protection·2019
Same author

Prolonged Microgravity Affects Human Brain Structure and Function.

AJNR. American journal of neuroradiology·2019

Area of Science:

  • Magnetic Resonance Imaging
  • Spectroscopy

Background:

  • Spectral localization techniques are crucial for isolating signals from specific regions in Magnetic Resonance Imaging (MRI).
  • Two primary classes of spectral localization exist: phase encoding and frequency selective radiofrequency (RF) pulses.
  • Artifacts like spatial misregistration can compromise spectral data accuracy, particularly in smaller regions using certain RF pulse methods.

Purpose of the Study:

  • To review and categorize existing methods for spectral localization in MRI.
  • To introduce and analyze Chemical Shift Imaging (CSI) as a representative phase encoding technique.
  • To derive an analytical expression for the point spread function in CSI, quantifying signal accuracy.

Main Methods:

  • Review of spectral localization techniques, categorizing them into phase encoding and frequency selective RF pulse methods.

Related Experiment Videos

  • Detailed presentation of Chemical Shift Imaging (CSI) as an example of phase encoding.
  • Derivation of the point spread function for CSI to define the relationship between observed and true signals.

    • Main Results:

    • Identification of spatial misregistration as a significant artifact in frequency selective RF pulse methods, impacting 31P spectra.
    • Development of an analytical expression for the point spread function in CSI, enabling quantitative assessment of localization accuracy.
    • Demonstration of CSI's applicability in one, two, and three dimensions for spectral localization.

    Conclusions:

    • Phase encoding techniques, exemplified by CSI, offer robust spectral localization with quantifiable accuracy.
    • CSI effectively illustrates the principles of phase encoding for spectral localization in MRI.
    • The derived point spread function provides a critical tool for understanding and optimizing CSI performance across various dimensions.