Hydrophobicity--getting into hot water
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Updated: Aug 31, 2026

Rendering SiO2/Si Surfaces Omniphobic by Carving Gas-Entrapping Microtextures Comprising Reentrant and Doubly Reentrant Cavities or Pillars
Published on: February 11, 2020
1Department of Haematology, University of Cambridge Clinical School, Wellcome Trust/MRC Building, Hills Road, CB2 2XY, Cambridge, UK. am12@mrc-lmb.cam.ac.uk
Abstract:
In his famous 1959 review, Walter Kauzmann clarified important features of the thermodynamic stabilities of proteins. The hydrophobic effect is recognised as an important contributor to the stability of proteins and an important determinant of their structural patterns. As generally understood, it depends on the unusual properties of cold water and its interactions with nonpolar solutes. Here we comment on the relationship between this paradigm and the stabilities and structures of proteins from thermophilic organisms.
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