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Published on: January 6, 2011
Bilateral subthalamic nucleus deep brain stimulation for advanced PD: correlation of intraoperative MER and
George J Counelis1, Tanya Simuni, Mark S Forman
1Department of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA.
Abstract:
This postmortem study correlated intraoperative subthalamic nucleus (STN) deep brain stimulation (DBS) placement and postoperative magnetic resonance imaging (MRI) with autopsy findings in a patient who died suddenly 4 days postoperatively from a pulmonary embolism. The study demonstrates that (1) MRI stereotactic localization combined with microelectrode recording (MER) is an accurate way to target STN; (2) multiple MER tracts do not cause significant injury to the brain; and (3) postoperative MRI accurately demonstrates location of the DBS electrodes.
