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Updated: Aug 31, 2026

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Published on: July 24, 2016
[Adult cases of viral meningitis caused by echovirus type 13]
Hiromi Tsutsui1, Tadanori Hamano, Miho Toho
1Second Department of Internal Medicine, Fukui Medical University.
Abstract:
Adult cases of viral meningitis caused by echovirus type 13 (E13) were studied. E13 was isolated from 8 of 11 adult patients (73%) with viral meningitis between April and September 2002 in Fukui Prefecture. The mean age was 27.4 +/- 6.4 years (4 males and 4 females). The disease was prevalent among adults, especially younger adults as well as children. The symptoms and signs were as follows; headache (100%), fever (100%), nausea and/or vomiting (88%), Kernig's sign (88%), and increased deep tendon reflexes (50%). The average cell counts in cerebrospinal fluid (CSF) were 118 +/- 111/mm3. Of the 2 patients, polynuclear cells were dominant during the early phase of the disease. The prognosis was good. Since May 2002, the number of patients with viral meningitis caused by E13 has rapidly increased. Most of the reported patients were children. We should consider the possibility of E13 infection as a cause of adult viral meningitis.
Insights
Echovirus type 13 (E13) caused viral meningitis in 73% of adult patients studied in 2002. This study highlights E13 as a significant cause of adult meningitis, with common symptoms including headache and fever.
Area of Science:
- Virology
- Neurology
- Infectious Diseases
Context:
- Echovirus type 13 (E13) outbreaks have been noted, primarily affecting children.
- Adult viral meningitis cases require etiological investigation.
Purpose:
- To investigate the prevalence and clinical characteristics of echovirus type 13 (E13) infections in adult patients with viral meningitis.
Summary:
- Echovirus type 13 (E13) was identified in 73% of 11 adult viral meningitis cases in Fukui Prefecture between April and September 2002.
- Patients, with a mean age of 27.4 years, presented with headache (100%), fever (100%), nausea/vomiting (88%), and Kernig's sign (88%).
- Cerebrospinal fluid analysis showed an average cell count of 118/mm3, with polynuclear cells dominant early in disease. Prognosis was favorable.
Impact:
- This study underscores the importance of considering E13 as a potential cause of viral meningitis in adults, not just children.
- Findings contribute to understanding the epidemiology and clinical presentation of E13 meningitis in an adult population.
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