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Updated: Jul 25, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
Accuracy of clinical detection of INO in MS: corroboration with quantitative infrared oculography
T C Frohman1, E M Frohman, P O'Suilleabhain
1Department of Neurology, University of Texas Southwestern Medical Center at Dallas, TX 75235, USA. elliot.frohman@utsouthwestern.edu
Abstract:
The authors compared the accuracy of clinical detection (by 279 physician observers) of internuclear ophthalmoparesis (INO) with that of quantitative infrared oculography. For the patients with mild adduction slowing, INO was not identified by 71%. Intermediate dysconjugacy was not detected by 25% of the evaluators. In the most severe cases, INO was not identified by only 6%. Oculographic techniques significantly enhance the precision of INO detection compared to the clinical exam.

