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Updated: Aug 14, 2026

Preparation of Pancreatic Acinar Cells for the Purpose of Calcium Imaging, Cell Injury Measurements, and Adenoviral Infection
Published on: July 5, 2013
Generation and modulation of cytosolic Ca2+ signals in pancreatic acinar cells: techniques and mechanisms
N J Dolman1, A V Tepikin, O H Petersen
1MRC Secretory Control Research Group, The Physiological Laboratory, University of Liverpool, Liverpool, UK L69 3BX. n.j.dolman@liv.ac.uk
Abstract:
Calcium is a ubiquitous signalling molecule, known to control a vast array of cellular processes. In order to retain stimulus fidelity, the cell encodes the increases in intracellular calcium in the form of oscillations that are regulated both temporally and spatially. Here, we review recent work, using the pancreatic acinar cell as a model system, on the mechanisms employed to generate and modulate cytosolic Ca(2+) signals, and the technical advances that have made these studies possible.
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