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Updated: Aug 31, 2026

Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells
Published on: September 18, 2016
New perspectives and emerging therapies for immune-mediated inflammatory disorders
1MCV & Associates Healthcare Consultants, Indianapolis, IN 46268, USA. cvpres@mcvassociates.com
Abstract:
Chronic inflammatory diseases, such as rheumatoid arthritis, psoriasis, and Crohn's disease, affect a large segment of the population in the United States. Recent research suggests that, in many inflammatory conditions, an inflammatory protein or cytokine, specifically tumor necrosis factor-alpha (TNF-alpha), appears to play an important role. Medications designed to treat these chronic inflammatory diseases, in addition to alleviating its symptoms, have become important therapeutic alternatives. This article will discuss specific Immune Mediated Inflammatory Disorders (I.M.I.D.), their treatment and management, as well as the current clinical application and potential future role of TNF-alpha antagonists as a common therapeutic modality.
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