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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
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Update: influenza activity--United States and worldwide, May-September 2003

    MMWR. Morbidity and Mortality Weekly Report
    |September 26, 2003
    PubMed

    Insights

    Influenza A(H3N2) viruses were common globally from May to September 2003, causing mild to moderate illness. Early influenza vaccination, starting in October, is recommended for North America due to its typical winter peak.

    Area of Science:

    • Virology
    • Epidemiology
    • Public Health

    Background:

    • Influenza A(H3N2) viruses were the predominant circulating strains globally during May-September 2003.
    • Influenza A(H1) and B viruses were detected less frequently during this period.
    • Sporadic detections of influenza A(H3N2), A(H1), and B viruses were noted in North America.

    Purpose of the Study:

    • To summarize global and United States influenza activity from May to September 2003.
    • To inform public health recommendations regarding influenza vaccination timing.

    Main Methods:

    • Surveillance data collection and analysis of reported influenza virus isolates.
    • Monitoring of disease activity levels associated with circulating influenza strains.

    Main Results:

    • Influenza A(H3N2) viruses were associated with mild to moderate disease activity worldwide.
    • Influenza A(H1) and B viruses were less frequently reported.
    • North American influenza activity showed sporadic detections of all three virus types.

    Conclusions:

    • The findings highlight the need for timely influenza vaccination campaigns.
    • Vaccination should commence in October and continue through December and the entire influenza season in North America, aligning with typical peak activity.
    • Continued global surveillance is essential for monitoring influenza trends and informing public health strategies.

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