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Updated: Feb 9, 2026

Oral Bacterial Infection and Shedding in Drosophila melanogaster
Published on: May 31, 2018
Bacterial RNase P as a potential target for novel anti-infectives
Paul S Eder1, Cynthia Hatfield, Agustin Vioque
1Message Pharmaceuticals Inc, 30 Spring Mill Drive, Malvern, PA 19355, USA.
Abstract:
The diversity of higher-order structure in ribonucleoprotein (RNP) complexes makes them amenable to small-molecule modulation of their biological function. This review will discuss why bacterial RNase P, a simple yet essential ubiquitous and highly conserved RNP enzyme, represents an excellent target for the discovery and development of novel antimicrobials.
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