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Updated: Aug 31, 2026

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
09:04

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products

Published on: September 9, 2016

Development for an efficient synthesis method of 2'-deoxyguanosine-C8 adducts with several amino/nitro-arenes

Takeji Takamura-Enya1, Satoko Ishikawa, Masataka Mochizuki

  • 1Cancer Prevention Basic Research Project, National Cancer Center Research Institute, 1-1 Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan.

Nucleic Acids Research. Supplement (2001)
|September 27, 2003
PubMed

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Direct alkylation of ammonia produces polyalkylated amines, along with a quaternary ammonium salt. To exclusively prepare primary amines, the azide synthesis method can be used.
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