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Coexistence of sarcoidosis and malignancy
William E Caras1, Thomas Dillard, Thomas Baker
1Department of Medicine, Pulmonary/Critical Care Service, Madigan Army Medical Center, Tacoma, WA, USA.
Southern Medical Journal
|September 30, 2003
Abstract:
In 1974, Brincker and Wilbek noted a statistically significant increase of malignant tumors among sarcoid patients and speculated that immunologic deficiencies stemming from sarcoidosis may predispose such patients to malignancy. In this article, we describe three additional cases of sarcoidosis and coexisting malignancy. The temporal presentation, radiographic features, and histologic findings are discussed in detail. The evidence for and against a proposed link between sarcoid and malignancy is reviewed.