Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Effect of coupled oscillations on microbubble behavior.

John S Allen1, Dustin E Kruse, Paul A Dayton

  • 1Department of Biomedical Engineering, University of California at Davis, One Shields Avenue, Davis, California 95616-5294, USA.

The Journal of the Acoustical Society of America
|September 30, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Volumetric Ultrasound Imaging Based on 4096-Element Large-Aperture 2D Array.

IEEE transactions on ultrasonics·2026
Same author

Deep Learning for scaling large-aperture photoacoustic computed tomography : From single fingers to the human hand.

Ultrasonics·2026
Same author

From Physical Therapy to Pioneering Molecular Imaging Instrumentation: Christine Mona and Johannes Czernin talk with Katherine Ferrara.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Ultrasound-Mediated Gene Therapy in Alzheimer's Disease Validated through In Vivo PET Imaging.

bioRxiv : the preprint server for biology·2026
Same author

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases.

Annals of neurology·2025
Same author

Improving real-time ultrasound spine imaging with a large-aperture array.

Science advances·2025
Same journal

Interaction of near-wall bubble arrays with acoustic waves induced by an oscillating rigid wall.

The Journal of the Acoustical Society of America·2026
Same journal

Ultra-broadband underwater acoustic projector based on transverse resonance orthogonal beam (TROB) mode and acoustic matching layer technique.

The Journal of the Acoustical Society of America·2026
Same journal

Fine-scale quantitative analysis of bowhead whale (Balaena mysticetus) song shows varying stability of song types.

The Journal of the Acoustical Society of America·2026
Same journal

High-resolution depth estimation for multiple wideband sources in deep sea via sparse Bayesian learninga).

The Journal of the Acoustical Society of America·2026
Same journal

Depression markers in speech: An approach based on tract variables dynamics.

The Journal of the Acoustical Society of America·2026
Same journal

The oyster toadfish (Opsanus tau) alters active and diurnal calling amid vessel noise in New York City.

The Journal of the Acoustical Society of America·2026
See all related articles

The acoustic coupling of ultrasound contrast agent microbubbles significantly alters their nonlinear scattering. Smaller microbubbles are more affected by coupling, impacting diagnostic imaging signal strength and spectral peaks.

Area of Science:

  • Acoustics
  • Biomedical Engineering
  • Medical Imaging

Background:

  • Ultrasound contrast agents are microbubbles used in diagnostic imaging.
  • Their nonlinear acoustic scattering is key to imaging applications.
  • Understanding microbubble interactions is crucial for optimizing contrast agent performance.

Purpose of the Study:

  • To theoretically investigate the coupled oscillations of microbubble pairs.
  • To analyze how different initial radii and separation distances affect microbubble behavior.
  • To quantify the impact of coupling on acoustic scattering signatures for imaging.

Main Methods:

  • Utilized radial equations in the monopole approximation for theoretical analysis.
  • Employed an energy balance approach for the system.

Related Experiment Videos

  • Performed numerical investigations of coupled microbubble pairs with varying radii and separation distances.

    • Main Results:

    • Smaller microbubbles are more substantially affected by coupling than larger ones when driven appropriately.
    • A 1.0-micron radius agent coupled with a 2.2-micron radius agent showed a ~10 dB difference in second harmonic output.
    • Subharmonic spectral peaks decreased by ~19 dB for coupled 1.5- and 2.2-micron agents.

    Conclusions:

    • Microbubble coupling significantly influences radiated pressure and spectral power.
    • These coupling effects are critical considerations for ultrasound contrast agent imaging.
    • The findings provide insights into optimizing microbubble behavior for enhanced diagnostic imaging.