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Fluorine-18 Fluorodeoxyglucose Accumulation in Blastomyces dermatitidis-Associated Inflammation in a Dog
Cary L. Matwichuk1, Gregory B. Daniel, Larissa A. Bowman
1Departments of Small Animal Clinical Sciences and Pathology, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA
Abstract:
Whole-body positron emission tomography (PET) imaging with fluorine-18 fluorodeoxyglucose (F-18 FDG) was performed in a dog with blastomycosis. Prior to PET scanning, blastomycotic lesions had been identified in both eyes, lungs, and tracheobronchial lymph nodes. Increased F-18 FDG uptake was present in these sites in addition to multiple organs without previous clinical evidence of disease. All sites of F-18 FDG uptake were confirmed histologically to be blastomycotic granulomas. F-18 FDG-PET scanning may be useful for defining the extent of fungal disease and detecting persistent foci of infection.