Related Experiment Video
Updated: Aug 30, 2026

Separation of Avian Preovulatory Follicle Granulosa and Theca Cell Layers for Downstream Applications
Published on: October 25, 2024
FET-1: a novel W-linked, female specific gene up-regulated in the embryonic chicken ovary
Kirsty J Reed1, Andrew H Sinclair
1Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Victoria, Australia.
Abstract:
A differential expression screen for sex-determining genes in the embryonic chicken gonad revealed a novel gene called Female Expressed Transcript 1 (FET-1). Fluorescent in situ hybridization analysis mapped FET-1 to the female specific W chromosome. Whole mount in situ hybridization showed that FET-1 expression was restricted to females and up-regulated in the cortex of the left gonad during the sex-determining period. Female specific expression was also observed in the embryonic caudal somites, neural tube and waste collection ducts.
Related Concept Videos
The Ratio of X Chromosome to Autosomes
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
Oogenesis
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
Oogenesis
Determination

