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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
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Elective coronary angiography and percutaneous coronary intervention during uninterrupted warfarin therapy

David B Jessup1, Andrew T Coletti, Joseph B Muhlestein

  • 1Division of Cardiology, University of Utah, Salt Lake City, Utah 84132, USA.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|October 1, 2003
PubMed

Insights

Warfarin anticoagulated patients can safely undergo coronary angiography and intervention without stopping medication. This approach minimizes bleeding and clotting risks during cardiac procedures.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Interventional Cardiology

Background:

  • Managing patients on warfarin undergoing coronary angiography is challenging.
  • Balancing bleeding and thromboembolic risks is crucial.

Purpose of the Study:

  • To assess the safety and feasibility of coronary angiography and percutaneous coronary intervention (PCI) with uninterrupted warfarin therapy.

Main Methods:

  • Prospective enrollment of 23 warfarin-treated patients undergoing cardiac procedures.
  • Diagnostic coronary angiography and PCI performed with continuous warfarin.
  • Hemostasis achieved using AngioSeal or Perclose devices.

Main Results:

  • 19 diagnostic catheterizations and 6 PCIs were performed.
  • Mean INR was 2.4 (range 1.8-3.5).
  • No patient experienced myocardial infarction, major/minor bleeding, or other adverse events.

Conclusions:

  • Cardiac catheterization and PCI can be safely performed in patients on uninterrupted warfarin.
  • This strategy appears feasible and avoids complications.

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