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Updated: Aug 2, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
[Outline of general shock theory]
Abstract:
Being directly, extremely dangerously affected, the organism of man (and laboratory animals) automatically starts showing an ancient hypobiotic protective reaction in the form of unique torpid syndrome. However, hypobiotic conditions are evolutionarily alien to the superior brain formations. A functional conflict arises between the new and old regulatory systems. Increasing pathology of regulation forms the whole typical stereotypical shock syndrome with its dangerous pathological components and phase course. However, shock maintains the organism's vitality and saves it from immediate death after the damaging effect of the initial collapse. The results depend on the adequacy of anti-shock therapy, the degree of organism's biological reserve preservation and severity of organ deficiency.
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