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Updated: Aug 30, 2026

07:38
Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
Published on: June 6, 2025
[Myelofibrosis in patients with chronic myeloid leukemia treated with interferon-alpha]
Kumas Sotiris1, E A Semenova, A G Turkina
1Hematological Research Centre, 125187, Moscow.
Arkhiv Patologii
|October 2, 2003
Abstract:
Trepanobiopsies of the bone marrow were studied in 46 patients in a chronic phase of chronic myeloid leukemia in different periods after the beginning of interferon-alpha therapy. Progression of myelofibrosis was observed in 2 cases only. Regression of myelofibrosis was observed in 14 cases of 29 (34.2%). A negative correlation between reticulin myelofibrosis and response to therapy was found. Disappearance of diffuse reticulin myelofibrosis in all cases was followed by a cytogenetic response.
