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Magnetic resonance imaging in pseudotumor cerebri
M B Connolly1, K Farrell, A Hill
1Department of Paediatric Neurology, Columbia's Children's Hospital, Vancouver, B.C.
Developmental Medicine and Child Neurology
|December 1, 1992
Summary
Pseudotumor cerebri pathophysiology may involve brain water transport issues. MR imaging in children with this condition showed normal white matter, suggesting no significant increase in periventricular brain water content.
Area of Science:
- Neurology
- Radiology
- Pediatrics
Background:
- The exact cause of pseudotumor cerebri (PTC) remains unclear.
- Potential links to abnormal brain water transport have been suggested.
Purpose of the Study:
- To investigate brain water content in children diagnosed with pseudotumor cerebri.
- To explore the relationship between PTC pathophysiology and brain water dynamics.
Main Methods:
- Magnetic Resonance (MR) imaging was utilized.
- Seven pediatric patients with pseudotumor cerebri were included in the study.
Main Results:
- MR imaging revealed normal signal intensity in the white matter of all patients.
- These findings indicate that periventricular brain water content is not significantly elevated in pediatric PTC.
Conclusions:
- The study suggests that increased resistance to cerebrospinal fluid outflow may be balanced by increased brain stiffness in pediatric PTC.
- This equilibrium could be a result of elevated cerebral blood volume and/or interstitial pressure.