Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Effects on blood pressure decrease in response to PAF of Impatiens textori MIQ.

Yoshimi Ueda1, Hisae Oku, Munekazu Iinuma

  • 1School of Pharmaceutical Sciences, Mukogawa Women's University, Nishinomiya, Japan.

Biological & Pharmaceutical Bulletin
|October 2, 2003
PubMed
Summary

Flowers of Impatiens textori contain compounds that inhibit blood pressure drops caused by platelet activating factor (PAF). This suggests potential anti-allergy applications for this plant extract.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structural elucidation and virucidal properties of resveratrol octamers isolated from Vatica albiramis.

Journal of natural medicines·2025
Same author

Two novel resveratrol dimers from Vatica albiramis: structural elucidation and UV-induced formation.

Journal of natural medicines·2025
Same author

Phenolic and Iridoid Glycosides from <i>Leonurus cardiaca</i> L. and Their Effects on the α, δ, and γ Subtypes of the PPAR System-Including the Discovery of the Novel Phenylethanoid Cardiaphenyloside A and the Most Active 7-Chloro-6-desoxy-harpagide.

Molecules (Basel, Switzerland)·2025
Same author

Sodium polystyrene sulfonate as an additional contributing factor to repeated gastric ulcers among other multiple factors in a patient undergoing hemodialysis: a case report.

BMC nephrology·2024
Same author

Accelerated involution of germinal center in palatine tonsils in IgA nephropathy.

PloS one·2024
Same author

Extracts of <i>Musa basjoo</i> induce growth inhibition and changes in the protein expression of cell cycle control molecules in human colorectal cancer cell lines.

Oncology letters·2022

Area of Science:

  • Pharmacology
  • Natural Product Chemistry
  • Allergy Research

Background:

  • Platelet-activating factor (PAF) is a key mediator in allergic inflammatory responses.
  • Impatiens textori flowers are traditionally used, but their pharmacological properties are not well-understood.
  • Investigating natural compounds for anti-allergy potential is crucial for developing new therapeutics.

Purpose of the Study:

  • To investigate the anti-hypertensive effects of Impatiens textori flower extract.
  • To isolate and identify active compounds responsible for the observed effects.
  • To evaluate the potential of Impatiens textori as an anti-allergy agent.

Main Methods:

  • Extraction of Impatiens textori flowers using 35% ethanol.
  • Bioassay-guided fractionation to isolate active compounds.

Related Experiment Videos

  • Measurement of blood pressure response to PAF using a monitoring system.
  • Identification of isolated compounds using spectroscopic methods.

    • Main Results:

    • The 35% ethanol extract of Impatiens textori flowers demonstrated significant inhibition of PAF-induced blood pressure decrease.
    • Bioassay-guided fractionation led to the isolation of several flavones, including apigenin and luteolin.
    • Apigenin and luteolin were found to significantly inhibit the blood pressure decrease in response to PAF.
    • Nine compounds, including apigenin 7-glucoside, chrysoeriol, quercetin, and various kaempferol derivatives, were isolated for the first time from this plant.

    Conclusions:

    • Impatiens textori flowers possess compounds with significant anti-hypertensive activity against PAF.
    • The isolated flavones, particularly apigenin and luteolin, are likely responsible for the observed inhibitory effects.
    • These findings suggest that Impatiens textori flowers hold promise as a source for novel anti-allergy agents.