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Related Experiment Videos

Total thyroidectomy for benign thyroid disease.

Celso U M Friguglietti1, Chin S Lin, Marco A V Kulcsar

  • 1Division of Head and Neck Surgery, Brazilian Institute of Cancer Control, Santo Amaro University, Avenue Paulista 1159, Room J.1514, São Paulo, Brazil. frigugli@uol.com.br

The Laryngoscope
|October 2, 2003
PubMed
Summary

Total thyroidectomy is recommended for benign thyroid diseases like multinodular goiter and Graves disease. This approach reduces the risk of repeat surgeries and associated complications, ensuring safer patient outcomes.

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Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Thyroid Surgery

Background:

  • Total thyroidectomy use in benign thyroid conditions is debated.
  • Repeat thyroid surgery for recurrence carries a significantly higher complication risk (up to 20x).

Purpose of the Study:

  • To evaluate the efficacy and safety of total thyroidectomy for benign diseases, including multinodular goiter and Graves disease.
  • To provide evidence supporting the preference for total thyroidectomy in specific benign thyroid conditions.

Main Methods:

  • Retrospective analysis of 1789 thyroidectomy cases between June 1990 and December 2000.
  • Evaluation of indications, extent of surgery, cancer incidence, and complication rates.
  • Analysis of total thyroidectomy rates in nontoxic multinodular goiter, toxic multinodular goiter, recurrent multinodular goiter, and Graves disease.

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Main Results:

  • Total thyroidectomy was performed in 81.19% of nontoxic multinodular goiter and 49.18% of Graves disease cases.
  • Thyroid cancer was incidentally found in 16.62% of nontoxic multinodular goiter and 5.73% of Graves disease patients.
  • Permanent complications were comparable between total and non-total thyroidectomy for these benign conditions.

Conclusions:

  • Total thyroidectomy is the preferred treatment for multinodular goiter and Graves disease, especially with bilateral involvement.
  • This approach minimizes the need for future operations, thereby reducing risks associated with recurrent disease.
  • Safe performance of total thyroidectomy is crucial for achieving favorable patient outcomes.