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Updated: Aug 5, 2026

Whole-cell Patch-clamp Recordings from Morphologically- and Neurochemically-identified Hippocampal Interneurons
Published on: September 30, 2014
Interneuron Diversity series: Hippocampal interneuron classifications--making things as simple as possible, not
Gianmaria Maccaferri1, Jean-Claude Lacaille
1Feinberg School of Medicine, Department of Physiology, Northwestern University, Chicago, IL 60611, USA. g-maccaferri@northwestern.edu
Abstract:
The nervous system is made up of many specific types of neuron intricately intertwined to form complex networks. Identifying and defining the characteristic features of the many different neuronal types is essential for achieving a cellular understanding of complex activity from perception to cognition. So far, cortical GABAergic interneurons have represented the epitome of cellular diversity in the CNS. Despite the desperate need for effective classification criteria allowing a common language among neuroscientists, interneurons still evoke memories of Babel. Several approaches are now available to overcome the challenges and problems associated with the various classification systems used so far.
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