Subtractive antibody to a human immunosuppressive lymphokine affinity isolates a suppressive factor and blocks its

A Z Haghighi1, M K Cathcart

  • 1Section of Immunology, Cleveland Clinic Foundation, OH 44195.

Immunopharmacology
|July 1, 1992
PubMed
Summary

Researchers developed a subtractive antibody approach to isolate hybridoma suppressor factors (HSF). This method successfully purified HSF, revealing specific proteins responsible for suppressing immune cell activity.