Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dietary fat and postprandial lipids.

Tom A B Sanders1

  • 1Nutrition Food and Health Research Centre, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NN, United Kingdom. Tom.Sanders@kcl.ac.uk

Current Atherosclerosis Reports
|October 4, 2003
PubMed
Summary

Limiting dietary fat intake to 30g per meal can minimize postprandial lipemia, reducing cardiovascular disease risk. Specific fats, like stearic acid-rich ones and omega-3 fatty acids, show beneficial effects on lipid metabolism.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

APOE4 Genotype Exerts Greater Benefit in Lowering Plasma Cholesterol and Apolipoprotein B than Wild Type (E3/E3), after Replacement of Dietary Saturated Fats with Low Glycaemic Index Carbohydrates.

Nutrients·2018
Same author

Effects of exchanging carbohydrate or monounsaturated fat with saturated fat on inflammatory and thrombogenic responses in subjects with abdominal obesity: A randomized controlled trial.

Clinical nutrition (Edinburgh, Scotland)·2016
Same author

Weight loss, adipokines, and quality of life after sleeve gastrectomy in obese patients with stages 3-4 CKD: a randomized controlled pilot study.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2014
Same author

UK Food Standards Agency Workshop Report: carbohydrate and cardiovascular risk.

The British journal of nutrition·2010
Same author

Successful manipulation of the quality and quantity of fat and carbohydrate consumed by free-living individuals using a food exchange model.

The Journal of nutrition·2009
Same author

UK Food Standards Agency Workshop Report: the effects of the dietary n-6:n-3 fatty acid ratio on cardiovascular health.

The British journal of nutrition·2007

Area of Science:

  • Nutritional Science
  • Cardiovascular Health
  • Metabolic Research

Background:

  • Impaired chylomicron remnant clearance elevates atherosclerosis and cardiovascular disease risk.
  • High-fat meals (40-50g) induce significant postprandial lipemia, exacerbated by consecutive meals.
  • Sedentary behavior and obesity negatively impact postprandial lipid metabolism.

Purpose of the Study:

  • To investigate dietary fat intake effects on postprandial lipemia.
  • To explore the impact of different fatty acids and dietary patterns on lipid metabolism.
  • To understand the relationship between postprandial lipemia and cardiovascular risk factors.

Main Methods:

  • Analysis of postprandial lipemia following controlled fat intake.
  • Comparison of different dietary fats (stearic acid-rich, cocoa butter, oleate, trans-18:1) effects.
  • Evaluation of long-chain omega-3 and alpha-linolenic acid dietary enrichment.

Main Results:

  • Limiting fat intake to ~30g per meal may minimize postprandial lipemia.
  • Stearic acid-rich fats reduced postprandial lipemia and factor VII activated (FVIIa) increase compared to oleate.
  • Long-chain omega-3 fatty acids (≥3g/d) decreased postprandial lipemia, unlike alpha-linolenic acid.

Conclusions:

  • Dietary fat quantity and type significantly influence postprandial lipemia.
  • Specific fatty acids and omega-3s show potential in managing postprandial lipid responses.
  • Further research into adipocyte metabolism is crucial for understanding diet and lipid regulation.

Related Experiment Videos