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Published on: April 14, 2011
Nosocomial influenza in children
1Second Department of Pediatrics, P. & A. Kyriakou Children's Hospital, University of Athens, 11527, Athens, Greece. helen-maltezou@ath.forthnet.gr
Insights
Influenza causes severe respiratory illness and hospitalizations in children, leading to nosocomial outbreaks. Annual influenza vaccination is crucial for high-risk children, families, and healthcare workers to prevent spread and reduce costs, despite limited coverage.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Influenza is a primary cause of pediatric acute respiratory illness and hospitalizations during epidemics.
- Nosocomial influenza outbreaks pose significant morbidity and mortality risks, particularly in vulnerable pediatric populations.
- Healthcare workers and pediatric patients are key reservoirs for nosocomial influenza transmission.
Purpose of the Study:
- To highlight the importance of influenza in pediatric hospitalizations and nosocomial spread.
- To emphasize the role of rapid diagnostics and antiviral agents in influenza management.
- To advocate for enhanced influenza prevention strategies, including vaccination, in pediatric settings.
Main Methods:
- Review of current literature on pediatric influenza epidemiology and nosocomial outbreaks.
- Discussion of advancements in influenza diagnostics (antigen detection) and therapeutics (neuraminidase inhibitors).
- Analysis of the cost-effectiveness and importance of annual influenza vaccination for high-risk children, families, and healthcare workers.
Main Results:
- Influenza necessitates prompt testing in hospitalized children with compatible symptoms during epidemics.
- Rapid antigen detection and neuraminidase inhibitors represent significant management advances.
- Annual vaccination is a cost-effective strategy for preventing influenza-related illness, hospitalizations, and deaths.
Conclusions:
- Implementing timely influenza testing and outbreak control measures in hospitals is essential.
- Vaccination is the cornerstone for preventing nosocomial influenza outbreaks in pediatric populations.
- Increased vaccination coverage among high-risk children, families, and healthcare workers is critical despite proven cost-effectiveness.
Abstract:
Influenza is the most important cause of acute respiratory illness leading to hospitalization among children during community epidemics. This illness can cause extensive nosocomial outbreaks with serious morbidity and mortality among specific groups of children. Paediatric patients with community-acquired influenza and healthcare workers are the main reservoir for the nosocomial spread of the virus. During epidemics in the community, testing for influenza should be requested in all children with compatible symptoms admitted in the hospital, and measures should be introduced for the prevention or early control of an outbreak. Recent advances in the management of influenza include rapid diagnoses based on antigen detection and the identification of the new neuraminidase inhibitors zanamivir and oseltamivir. Annual vaccination against influenza of children with high-risk conditions, their family members and healthcare workers is the principle measure for the prevention of nosocomial outbreaks. Although vaccination against influenza appears to be cost-effective at all ages in terms of prevention of illness, related hospitalizations, deaths, reduction of healthcare costs and productivity loss, vaccination coverage among target groups is limited.
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