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[Effect of Smilax china on adjunctive arthritis mouse]
Yongning Lü1, Dongsheng Chen, Jungang Deng
1Affiliated Xiehe Hospital, Tongji Medical College, China University of Science and Technology, Wuhan 430030.
Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials
|October 11, 2003
Abstract
Objective:
To study the therapeutic action of decoction of Smilax china L. on adjunctive arthritis(AA) mouse and its mechanism.
Methods:
To observe the change of secondary inflammation, thymus and spleen weights, T cell subgroup, B cell, NK cell.
Results:
The decoction (90, 180 g.kg-1) intragastric injection (ig) could significantly inhibit AA mouse's secondary inflammatory swelling, reduce thymus and spleen weights, decrease CD4/CD8, but had little influence on B Cell.
Conclusions:
The decoction has therapeutic action by regulating cell-mediated immunity, but has little effect on humoral immunity.