Related Experiment Videos
Influence of alpha-adrenoceptor blockade with thymoxamine on changes in pupil diameter and accommodation produced by
Current Medical Research and Opinion
|January 1, 1977
Abstract:
In a study in 12 healthy volunteers, local instillation of thymoxamine eye-drops (0.2%) completely reversed the mydriasis produced by ephedrine (5%) but not that produced by ephedrine (5%) together with tropicamide (0.5%). Small but significant changes in accommodation were found with ephedrine and reversed by thymoxamine, suggesting that they were mediated through alpha-adrenoceptor activity. The thymoxamine eyedrops were well tolerated.