Dynamic multivalent lactosides displayed on cyclodextrin beads dangling from polymer strings
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Updated: Aug 30, 2026

Formation of Biomembrane Microarrays with a Squeegee-based Assembly Method
Published on: May 8, 2014
Alshakim Nelson1, J Fraser Stoddart
1California NanoSystems Institute and the Department of Chemistry and Biochemistry, University of California, Los Angeles, 405 Hilgard Avenue, Los Angeles, California 90095, USA.
Abstract:
[reaction: see text] Lactose-appended cyclodextrin derivatives have been synthesized and threaded onto hydrophobic polymers in aqueous solution to form dynamic multivalent lactosides for binding to lectins. The threading process, which proceeds quickly, can be observed by one- and two-dimensional NMR spectroscopies.
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