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Endogenous superoxide dismutase activity in two Babesia species
P Becuwe1, C Slomianny, A Valentin
1INSERM U42, Villeneuve d'Ascq, France.
Parasitology
|October 1, 1992
Abstract:
Babesia hylomysci and B. divergens were studied for superoxide dismutase (SOD) activity by enzyme assay and isoelectric focusing (IEF). In the two Babesia species, parasite-associated SOD is cyanide-insensitive and inhibited by H2O2, indicating that iron is the cofactor metal. Measurements of SOD activity from purified parasites show that the SOD activity detected in Babesia is, for the main part, due to an endogenous enzyme.