Clinical signs and mechanism of supermethrin intoxication in sheep

Three Slovak Merino sheep, weighing 38, 40 and 41 kg, were given single doses of 1500, 2700 or 3000 mg supermethrin/kg body weight. Clinical signs of intoxication were observed, and after death or sacrifice free cyanide levels were determined in the rumen contents and liver. The sheep that received 3000 mg supermethrin/kg had 7.2 and 0.58 mg cyanide/kg in the rumen contents and liver, respectively; the sheep that received 2700 mg supermethrin/kg had 5.8 and 0.52 mg cyanide/kg in the rumen contents and liver, respectively; whereas the sheep given 1500 mg supermethrin/kg had no free cyanide detected in the rumen contents or liver.