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[Psychological and neuropsychological problems in multiple sclerosis].
Daniel Béquet1, Hervé Taillia, Patrick Clervoy
1Service de neurologie, HIA du Val de Grâce, 74 Boulevard de Port Royal-75005 Paris.
Bulletin De L'Academie Nationale De Medecine
|October 15, 2003
Summary
Cognitive disorders, affecting 60% of multiple sclerosis patients, include memory loss and slowed processing. Brain lesions correlate with these deficits, necessitating neuropsychological rehabilitation.
Area of Science:
- Neurology
- Neuropsychology
- Psychiatry
Context:
- Multiple sclerosis (MS) frequently causes cognitive and psychiatric impairments.
- Approximately 60% of MS patients exhibit cognitive dysfunction.
- Subcortical white matter dementia is a potential term for MS-related cognitive decline.
Purpose:
- To investigate the prevalence and nature of cognitive and psychiatric disorders in multiple sclerosis.
- To explore the correlation between magnetic resonance imaging (MRI) findings and neuropsychological test results in MS patients.
- To highlight the importance of neuropsychological rehabilitation and symptomatic treatments for MS.
Summary:
- Cognitive deficits in MS include forgetfulness, reduced processing speed, impaired attention, and slowed thinking.
- Psychiatric disturbances such as depression and personality changes are also prevalent in MS.
- Total lesion load on MRI, cerebral atrophy, and corpus callosum lesions predict cognitive deficits.
Impact:
- Findings underscore the significant impact of MS on cognitive function and mental health.
- Demonstrates the utility of correlating neuroimaging with neuropsychological assessments for MS.
- Emphasizes the need for integrated treatment approaches including rehabilitation for MS patients.