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Updated: Aug 30, 2026
Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation
Published on: December 26, 2017
[Comparative evaluation of effects of p-tyrosol and Rhodiola rosea extract on bone marrow cells in vivo]
I A Pashkevich1, Iu A Uspenskaia, V V Nefedova
1Department of Animal Anatomy and Physiology, Krasnoyarsk State Medical Agricultural University, pr. Mira 88, Krasnoyarsk, 660049 Russia.
Abstract:
The effects of p-tyrosol and Rhodiola rosea extract on the hemopoietic system were compared on a model of subacute lead intoxication. No significant differences between the activity of two preparations were revealed by the study of plasma membrane blebbing, apoptosis, and necrosis processes in bone marrow. At the same time, p-tyrosol exhibited a more pronounced effect upon lipid peroxidation and offered significant protection against lead intoxication.
