Related Experiment Video
Updated: Jul 14, 2026
07:29
Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
Plasma lipoprotein concentrations in ethnic populations
1Division of Cardiology, The David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue; 47-123 CHS, Los Angeles, CA 90095-1679, USA. kwatson@mednet.ucla.edu
Current Cardiology Reports
|October 16, 2003
Summary
Genetic and environmental factors influence plasma lipoprotein levels, leading to ethnic variations. This review examines these lipid differences and their impact on coronary heart disease risk.
Area of Science:
- Cardiovascular Science
- Genetics
- Epidemiology
Background:
- Plasma lipoprotein levels are influenced by a complex interaction of genetic and environmental factors.
- Reported differences in lipid levels exist between various ethnic groups.
- Conflicting data and limited research exist on ethnic variations in lipids and their relation to coronary heart disease (CHD) risk in specific populations.
Purpose of the Study:
- To review existing data on ethnic variations in plasma lipoproteins.
- To explore the potential impact of these variations on coronary morbidity and mortality.
Main Methods:
- Literature review of studies on ethnic variations in plasma lipoproteins.
- Analysis of data on lipid levels across different ethnic groups.
- Assessment of the association between lipoprotein levels and CHD risk in diverse populations.
Main Results:
- Summarizes available data on ethnic variations in plasma lipoproteins.
- Highlights the potential impact of these variations on coronary morbidity and mortality.
- Identifies gaps in current research regarding specific populations.
Conclusions:
- Ethnic variations in plasma lipoproteins are influenced by genetic and environmental factors.
- Understanding these variations is crucial for assessing coronary heart disease risk in diverse populations.
- Further research is needed to clarify the relationship between lipoproteins, ethnicity, and cardiovascular outcomes.
Related Concept Videos
01:18Lipids: Dietary Sources and Requirements
Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ meats, shellfish,...
01:29Cholesterol: Significance and Regulation
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
01:23Drug Concentrations: Measurements
Drug concentration is the quantity of a drug present in a biological sample. Measuring drug amounts in biological samples allows the clinician to understand how a drug is absorbed, distributed, metabolized, and excreted. Samples can be obtained through invasive or non-invasive methods. Invasive techniques involve surgical or parenteral interventions to gather blood, cerebrospinal fluid, or tissue biopsy. Conversely, non-invasive approaches provide samples like urine, feces, and saliva.
Plasma —...
Plasma —...
01:25Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
01:17Pharmacokinetics in Pediatric Patients: Drug Distribution
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...