Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Passive immunization as prophylaxis: when and where will this work?

Paul M Dunman1, Mirjana Nesin

  • 1Bacterial Vaccines, Wyeth, 401 N. Middletown Road, Pearl River, NY 10965, USA. dunmanp@wyeth.com

Current Opinion in Pharmacology
|October 16, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploration of a benzothiophene scaffold for use as adjuvants with β-lactam antibiotics against methicillin-resistant <i>Staphylococcus aureus</i>.

RSC medicinal chemistry·2026
Same author

Salivary gland tissue chip screening identifies candidate radioprotective drugs.

Communications medicine·2025
Same author

Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments.

mSphere·2025
Same author

Phenyl urea based adjuvants for β-lactam antibiotics against methicillin resistant Staphylococcus aureus.

Bioorganic & medicinal chemistry letters·2025
Same author

Development of phenyl-urea-based small molecules that target penicillin-binding protein 4.

Chemical biology & drug design·2024
Same author

Development of Next-Generation COVID-19 Vaccines: Biomedical Advanced Research and Development Authority (BARDA-)-Supported Phase 2b Study Designs.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2024
Same journal

Targeting the ischemic cascade: Review on approved and investigational stroke therapies.

Current opinion in pharmacology·2026
Same journal

Senotherapeutic strategies for ovarian aging: Mechanistic insights and translational perspectives.

Current opinion in pharmacology·2026
Same journal

Chrono-immunotherapy in precision oncology: Circadian control of the tumor microenvironment and time-of-day optimization of immune checkpoint blockade.

Current opinion in pharmacology·2026
Same journal

Methotrexate: Integrating molecular pharmacology, systems toxicology, and precision rescue strategies.

Current opinion in pharmacology·2026
Same journal

Acupuncture and non-invasive neuromodulation-induced neuro-endocrine-immune changes associated with the amelioration of depression-like behaviors: A systematic review of animal studies.

Current opinion in pharmacology·2026
Same journal

Alopecia areata: Mechanisms, targeted therapies, and translational challenges.

Current opinion in pharmacology·2026
See all related articles

Passive immunoprophylaxis, using antibodies, helps prevent infections and neutralize toxins. This therapy remains a vital option when other treatments are unavailable for various pathogens.

Area of Science:

  • Immunology
  • Infectious Diseases
  • Pharmacology

Background:

  • Passive immunoprophylaxis involves administering exogenous antibodies to prevent infections, neutralize toxins, or treat hypogammaglobulinemia.
  • Current treatments for many pathogens remain limited despite advances in chemotherapy and vaccines.
  • The scope of passive immunization can be expanded to encompass immune system modulators.

Purpose of the Study:

  • To define and explore the applications of passive immunoprophylaxis.
  • To highlight its relevance as a therapeutic strategy for infectious diseases.

Main Methods:

  • Review of existing literature on passive immunoprophylaxis.
  • Analysis of antibody administration (polyclonal and monoclonal) for therapeutic and prophylactic purposes.

Related Experiment Videos

Main Results:

  • Passive immunoprophylaxis is a defined medical intervention using antibodies.
  • It serves critical roles in preventing infections and managing specific conditions like hypogammaglobulinemia.
  • The therapeutic potential extends to various pathogens where other treatments are lacking.

Conclusions:

  • Passive immunoprophylaxis is a crucial therapeutic option for preventing infections and neutralizing toxins.
  • Its application is particularly important for immunocompromised individuals and in cases of limited treatment alternatives.
  • Broader applications, including immune modulators, warrant further investigation.