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Synthesis of retro acyl carrier protein (74-65) fragment on a new glycerol based polystyrene support
P G Sasikumar1, K S Kumar, V N Rajasekharan Pillai
1School of Chemical Sciences, Mahatma Gandhi University, Kottayam 686560, India.
Protein and Peptide Letters
|October 17, 2003
Abstract:
Retro-ACP (74-65) fragment was synthesized on a novel 4% tri-(propylene glycol) glycerolate diacrylate cross-linked polystyrene (PS-TRPGGDA) support. The peptide is grown from the functional site present in the cross-linker, which makes it unique and cost-effective among other styrene based polymer supports. A comparative study with Merrifield resin indicates high yield and purity of the peptide synthesized on the novel support.
