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Model of reversible cerebral ischemia in a monkey model
Charles A Jungreis1, Edwin Nemoto, Fernando Boada
1Department of Radiology, University of Pittsburgh Medical Center, PA 15213, USA.
AJNR. American Journal of Neuroradiology
|October 17, 2003
Abstract:
We have developed a model of reversible cerebral ischemia in a high-level nonhuman primate. By using endovascular techniques, the posterior cerebral artery is permanently occluded with coils, and the ipsilateral middle cerebral artery is temporarily occluded with a balloon. The balloon can be deflated and/or removed to reestablish flow at precise time intervals. Functional imaging of the brain can be performed during occlusion and reperfusion, since the balloon can be deflated or removed in a scanner.