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Related Experiment Videos

Buckwheat-induced anaphylaxis: a case report.

A E Davidson1, M A Passero, G A Settipane

  • 1Division of Allergy and Immunology, Rhode Island Hospital, Providence.

Annals of Allergy
|November 1, 1992
PubMed
Summary
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Buckwheat allergy can cause severe reactions like anaphylaxis, even in those not allergic to wheat. This study highlights buckwheat as a distinct food allergen, separate from common grains.

Area of Science:

  • Food allergy research
  • Immunology
  • Occupational health

Background:

  • Buckwheat (Fagopyrum schulentum) is a pseudocereal, not related to wheat.
  • Buckwheat flour is a common wheat substitute in various food products.
  • Occupational exposure to buckwheat flour can trigger respiratory and skin reactions.

Observation:

  • A patient experienced urticaria and hypotension after consuming buckwheat crepes.
  • Skin prick testing showed a strong positive reaction to buckwheat.
  • Negative reactions were observed for wheat, egg white, and milk.

Findings:

  • Radioallergosorbent test (RAST) for anti-buckwheat IgE was strongly positive.
  • Buckwheat ingestion is identified as a potential cause of food-related anaphylaxis.

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  • No cross-reactivity was observed between buckwheat and wheat allergy.

    • Implications:

    • Buckwheat allergy is a distinct clinical entity requiring specific diagnostic approaches.
    • Patients with buckwheat allergy should avoid buckwheat-containing foods.
    • Further research is needed to understand the prevalence and mechanisms of buckwheat allergy.