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Benzotriazole: an ideal synthetic auxiliary
Alan R Katritzky1, Boris V Rogovoy
1Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, P. O. Box 177200, Gainesville, FL 32611-7200, USA. katrinsky@chem.ufl.edu
Abstract:
Benzotriazole is a synthetic auxiliary that offers many advantages. It is inexpensive, odorless, and stable. A benzotriazole group is easily introduced, activates molecules towards numerous transformations, and can be removed easily at the end of the reaction sequence. This Concept provides some recent examples of the synthetic application of benzotriazole methodology and is intended to draw attention to the versatile applications of benzotriazole in organic chemistry.
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