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Updated: Aug 30, 2026

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
Published on: April 5, 2011
[Cardiotoxicity of amantadine in acute poisoning: a case report]
Dorota Szpak1, Wiesław Piotrowski, Barbara Groszek
1Klinika Toksykologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie, WSS im. L. Rydygiera 31-826 Kraków, Os. Złotej Jesieni 1.
Abstract:
We report the case of an adolescent, 15-year-old woman, who ingested 4.0 g of amantadine in a suicide attempt 2 hours before admission. She developed central nervous system symptoms including confusion and psychomotor agitation. The main cardiovascular symptoms were due to disturbances in atrioventricular conduction and propagation of stimuli in sinus node. All cardiovascular symptoms disappearanced after 12 hours of admission, CNS symptoms were observed 48 hours. No other systems were involved. She was discharged in a good state on day 5th.
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