Related Experiment Videos
Basal cell adenoma-an unusual presentation
Manikkapurath Hemachandran1, Anupam Lal, Kim Vaiphei
1Department of Pathology and Radio-diagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Annals of Diagnostic Pathology
|October 23, 2003
Summary
Basal cell adenoma, a rare salivary gland neoplasm, can present as a parapharyngeal mass originating from minor salivary glands. This case highlights its unusual location and histomorphology.
Area of Science:
- Pathology
- Oncology
Background:
- Basal cell adenoma (BCA) is an uncommon salivary gland neoplasm, typically found in parotid glands.
- This report details an unusual presentation of BCA in a minor salivary gland.
Observation:
- A large, slowly progressing parapharyngeal mass was identified.
- Histopathology confirmed a well-encapsulated mass with characteristic features.
- Immunohistochemistry revealed positivity for pancytokeratin, S-100, smooth muscle actin, carcinoembryonic antigen, and vimentin.
Findings:
- The tumor exhibited features of myoepithelial cell involvement.
- Ultrastructural analysis showed reduplicated basal laminae and cytoplasmic inclusions.
- This represents the first reported case of basal cell adenoma presenting as a parapharyngeal mass.
Implications:
- This case underscores the potential for basal cell adenomas to arise in minor salivary glands.
- It expands the known clinical presentations of this rare salivary gland tumor.
- Highlights the importance of considering rare diagnoses in unusual anatomical locations.